The collection is organized into ten series: Writing, Correspondence, Family, Activism, Teaching, Financial, Photographs, Audiovisual Material, Printed Material, and Ephemera. Specifically, the collection focuses on women's studies, sexual and gender identity, sexuality, and Pratt's fight against racism, sexism, imperialism and other forms of intolerance. Materials in the collection document Pratt's work as a teacher, poet, writer, and activist. The Minnie Bruce Pratt Papers contain materials dating from the 1870s to 2005, with the bulk of the collection dating between 19. Notable correspondents include Mumia Abu-Jamal, Dorothy Allison, Judith Arcana, Elly Bulkin, Chrystos, Holly Hughes, Audre Lorde, Adrienne Rich, and Mab Segrest. Other series in the collection are Correspondence Family, consisting of early correspondence, mementos, photographs, and genealogical information Activism, files of newspaper clippings, fliers, and correspondence related to Pratt's grass roots organizing Teaching, Financial, Photographs, Audiovisual Material, Printed Material, and Ephemera.

Major works represented are Pratt's poetry and essay collections The Sound of One Fork, We Say We Love Each Other, Crime Against Nature, Rebellion: Essays 1980-1991, S/HE, Walking Back Up Depot Street, and The Dirt She Ate. The series also contains materials pertaining to the outside funding from grants and speaking appearances that Pratt obtained to support herself as a writer. A Writing Series comprises drafts, proofs, and galleys related to Pratt's major works through 2003, as well as materials related to shorter pieces by Pratt, reviews, print interviews, materials related to Pratt's editorial work, and personal journals. The collection dates primarily between 19 and focuses on women's studies, sexual and gender identity, sexuality, and Pratt's fight against racism, sexism, imperialism and other forms of intolerance. As of 2008, Pratt resides with longtime partner, transgender activist and author Leslie Feinberg. Pratt has two sons, Ransom Weaver and Ben Weaver, from her marriage (1966-1975). Pratt frequently makes speaking appearances at conferences and universities across the United States.

Pratt began teaching and grass roots organizing in North Carolina in the 1970s, and has continued her work as a professor and activist through 2008, the time of this writing. An award-winning poet, Pratt has published collections of both poetry and essays. She received a bachelor's degree in English from the University of Alabama in Tuscaloosa and a doctorate in English Literature from the University of North Carolina at Chapel Hill. Minnie Bruce Pratt was born in Selma, Alabama in 1946 and raised in nearby Centreville.

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